Most males consume NSAIDs for the sake of musculoskeletal pain, primarily back pain. 85% of the population experiences recurring back pain episodes at some point in their lifetime. A link exists between NSAID drugs and hormone disruption which suppresses testosterone in males. Ibuprofen induces a state of compensated hypogonadism within fourteen days of regular use. In other worlds, ibuprofen quickly reduces the ability for the male body to produce the masculine hormone known as testosterone.